Transradial: Registry of Transradial Access for Angiography.

Disruption of the cerebral blood flow during acute ischemic stroke disrupts oxygen and glucose delivery to cells, leading to injury of cellular organelles such as mitochondria. Mitochondrial dysfunction has been recognized as one of the major contributors to neuronal death after stroke. We are studying a treatment called mitochondrial transplant, where a patient's healthy mitochondria are injected into an artery in the brain that supplies tissue damaged from an ischemic stroke. This treatment is based on a biological process called mitochondrial transfer which occurs naturally between different brain cell types during stroke. The objective of this first-in-human-brain study is to understand if the healthy transplanted mitochondria are safely incorporated into the damaged brain cells, limit or prevent further neuronal injury, and possibly even restore function to damaged brain. This University of Washington will be the first institution to study this treatment in human stroke patients.

Read more about the trial at https://clinicaltrials.gov/ct2/show/NCT04998357